NiWO4 catalyzed expeditious synthesis of Pyranopyrazoles

Abstract

In this paper, a multicomponent green rapid method for synthesis of pyranopyrazoles is reported using NiWO4 in water in 15 min. Environment friendly features such as energy efficiency, aqueous medium, no hazardous solvent, no chromatography, in addition to the short reaction time, catalyst reusability and substrate tolerance without affecting yield proves the near perfectness of this method for synthesis of medicinally important pyranopyrazoles. NiWO4, ZnWO₄, and CuWO₄ have been synthesized using extract of plant Phyllantus amarus. The prepared catalysts have been characterized byXRD, EDX and SEM.