Sensor and antibacterial research of Mussaenda frondosa leaf extract assisted zinc oxide nanoparticles

Abstract

Leaf extract of Mussaenda frondosa is used to synthesise as-prepared nanostructured zinc oxide nanoparticles (ZnO NPs). The synthesised ZnO NPs were analysed using Transmission electron microscopy (TEM), Field emission scanning electron microscopy (FE-SEM), Energy dispersive X-ray spectroscopy (EDX), Ultraviolet-visible spectrophotometry (UV-VIS), X-ray diffractometry (XRD) and Fourier-transform infra-red spectroscopy (FTIR) to show its hexagonal Wurtzite structure with average crystallite size 14.03 nm. The study employed a modified ZnO NPs carbon paste electrode (ZnO NPs/CPE-MCPE) to examine the electrochemical behaviour of dopamine. These investigations demonstrated significant levels of selectivity and sensitivity for detecting dopamine (DA) in the presence of 0.2 M phosphate buffer solution (PBS) at pH 7.4. Antibacterial investigations following the agar cup diffusion studies revealed efficacy against the test pathogens namely S. aureus (Gram-positive) and Klebsiella sp. (Gram-negative).