Electrochemical investigation of 5-fluorouracil at ZnO modified carbon paste electrode

dc.contributor.author	Mamata Prabhugaonkar a
dc.contributor.author	Jyothi H. Kini b
dc.contributor.author	B.E. Kumara Swamy c
dc.contributor.author	L.S. Manjunatha
dc.date.accessioned	2026-04-15T04:33:51Z
dc.date.issued	2026-01-01
dc.description.abstract	In this study, a carbon paste electrode has been modified with ZnO nanoparticles (ZnO NPs) synthesized using the leaf extract of Tabernaemontana divaricata (T. divaricata) to serve as a sensor to detect 5-Fluorouracil (5-FU) through voltammetric techniques. X-ray diffractometry (XRD) confirmed the hexagonal Wurtzite structure of ZnO NPs with an average crystallite size of 10.28 nm. ZnO-modified carbon paste electrodes (ZnO/MCPE) showed excellent sensitivity and electrocatalytic performance relative to bare carbon paste electrodes (BCPE), achieving a lower detection limit (LOD) of 3.41 µM for the detection of 5-Fluorouracil. In the simultaneous detection of 5-FU and Sulfadiazine (SFZ), ZnO/MCPE exhibited a significantly higher current response, with well-elucidated peak potentials observed at 1.05 V and 0.86 V for 5-FU and SFZ, respectively.
dc.identifier.other	https://doi.org/10.1016/j.matlet.2025.139268
dc.identifier.uri	https://sxcgoa.ndl.gov.in/handle/123456789/56
dc.language.iso	en
dc.publisher	Materials Letters (Science Direct )
dc.relation.ispartofseries	402; 139268
dc.title	Electrochemical investigation of 5-fluorouracil at ZnO modified carbon paste electrode
dc.type	Article

Files

Now showing 1 - 1 of 1